Biophysics & Nanosciences­ „Physics of Life“

An­sel­met­ti Lab

Quan­ti­fi­ca­ti­on of selec­ti­ve and spe­ci­fic bio­mole­cu­lar in­ter­ac­tion me­cha­nisms and their as­so­cia­ted dy­na­mic and re­gu­la­ted cel­lu­lar pro­per­ties and pro­ces­ses in bio­lo­gy, me­di­ci­ne and tech­ni­cal Na­no­Bio­Med ap­p­li­ca­ti­ons.

The lab was es­tab­lished in 2000 by Dario An­sel­met­ti in the Fa­cul­ty of Phy­sics and is in­te­gra­ted in the Bie­le­feld In­sti­tu­te for Na­no­sci­ence (BINAS). In 2003, the lab in­itia­ted one of the first hands-​on ex­pe­ri­ence sci­ence labs for child­ren edu­ca­ti­on in phy­sics – see also teutolab-​physik.

Na­no­sci­ence view to the Phy­sics of Life

Using cutting-​edge na­no­me­cha­ni­cal single-​molecule and single-​cell me­tho­do­lo­gy like ato­mic force mi­cro­scopy, op­ti­cal and ma­gne­tic tweezers, and micro-​ and na­no­flui­dic lab-​on-a-chip de­vices, we in­ves­ti­ga­te the phy­si­cal frame­work of how mole­cu­les and cells in­ter­act. The main focus lies on the mole­cu­lar in­ves­ti­ga­ti­on of the struc­tu­ral and func­tio­nal aspects of mole­cu­lar self-​assembly, bio­lo­gi­cal re­co­gni­ti­on and re­gu­la­ti­on, glycobiology-​biophysics of ma­ri­ne or­ga­nisms, na­no­po­res and na­no­mem­bra­nes, as well as fun­da­men­tal re­se­arch ap­p­li­ca­ti­ons in me­di­ci­ne for pro­spec­ti­ve tre­at­ment of can­cer, in­fec­tions and car­dio­myo­pa­thies.